Synthesis and Characterizations of B2O3-SiO2-Na2O Controlled-release Antibacterial Agent

doi:10.15541/jim20160395

Abstract

Abstract:

High temperature melting method has been used to synthesize B₂O₃-SiO₂-Na₂O controlled-release antibacterial agent on account of the functions that borate can inhibit the growth of bacteria and algae. The new inhibitor, a solid agent with controlled-release capability in water, is different from those liquid and gaseous antibacterial agents. In this study, the physicochemical properties of the inhibitor were characterized by XRD, SEM and FTIR. The concentrations of boron in solution were determined by using ICP-AES to determine the release capability of the inhibitor. Moreover the experiments of inhibitory circle and inhibitory rate were carried out to evaluate the antibacterial effects of the inhibitor on Escherichia Coli and Staphylococcus Aureus. The results indicate that the inhibitors present amorphous structure, with the content of [BO₃] and [BO₄] groups in the internal structure being affected by the amounts and the ratio of B₂O₃ and SiO₂. The agent surface is denser while the release rate decreases with the decrease of B₂O₃ amount. Furthermore, the antibacterial effect enhances with the increase of boron concentration. S. Aureus is more sensitive to the inhibitor than E. Coli. The inhibitor containing 55wt% of B₂O₃gets the best antibacterial effect , which exhibits better controlled-release than the others. The present results provide a reference for further research and industrial application of the antibacterial agent.

Key words: boron, controlled-release, antibacterial effect

CLC Number:

TQ174

SHI Rui-Rui, LI Meng, PEI Yuan-Sheng. Synthesis and Characterizations of B₂O₃-SiO₂-Na₂O Controlled-release Antibacterial Agent[J]. Journal of Inorganic Materials, 2017, 32(5): 529-534.

Figures/Tables 8

References 27

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Inhibitor	B₂O₃/wt%	Na₂O/wt%	SiO₂/wt%
1	70	12.4	17.6
2	65	11.5	23.5
3	60	10.6	29.4
4	55	9.8	35.2

Inhibitor	B₂O₃/wt%	Na₂O/wt%	SiO₂/wt%
1	70	12.4	17.6
2	65	11.5	23.5
3	60	10.6	29.4
4	55	9.8	35.2

Wavenumber/cm^-1	Corresponding characteristic vibration ascription
3423-3426	H-O stretching vibration peak
1413-1424	[BO₃] anti symmetrical stretching vibration peak
1071-1076	[BO₄] anti symmetrical stretching vibration peak
923-930	[BO₄] anti symmetrical stretching vibration peak
686-696	[BO₃] flexural vibration peak
451-466	Si-O-Si flexural vibration peak

Wavenumber/cm^-1	Corresponding characteristic vibration ascription
3423-3426	H-O stretching vibration peak
1413-1424	[BO₃] anti symmetrical stretching vibration peak
1071-1076	[BO₄] anti symmetrical stretching vibration peak
923-930	[BO₄] anti symmetrical stretching vibration peak
686-696	[BO₃] flexural vibration peak
451-466	Si-O-Si flexural vibration peak

Inhibitor	Boron /(mg·mL^-1)		E. coli			S. aureus
Inhibitor	Boron /(mg·mL^-1)	0.5	1	1.5	2	0.5	1	1.5	2
1	Diameter	<10	10±0.5	12±0.5	15±0.5	11±0.5	17±0.5	19±0.5	30±0.5
1	Sensitivity	–	+	+	+	+	++	++	+++
2	Diameter	<10	10±0.5	11±0.5	17±0.5	13±0.5	17±0.5	20±0.5	23±0.5
2	Sensitivity	–	+	+	++	+	++	++	+++
3	Diameter	<10	11±0.5	13±0.5	18±0.5	14±0.5	17±0.5	19±0.5	22±0.5
3	Sensitivity	–	+	+	++	+	++	++	+++
4	Diameter	<10	14±0.5	14±0.5	16±0.5	12±0.5	16±0.5	20±0.5	30±0.5
4	Sensitivity	–	+	+	++	+	++	+++	+++

Synthesis and Characterizations of B₂O₃-SiO₂-Na₂O Controlled-release Antibacterial Agent

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