Cubic Mesoporous Silica Thin Films Coated on Titanium to Induce Carbonated Hydroxyapatite Deposition

doi:10.15541/jim20150038

Abstract

Abstract:

Cubic mesoporous silica thin films were synthesized on pure titanium by dip-coating method and then their bioactivity were evaluated through the induced deposition of bone-like carbonated hydroxyapatite (CHA) layer in vitro. The composition, microstructure and morphology of the films were characterized by small-angel X-ray diffraction, Fourier transform infrared spectrum, nitrogen adsorption, electron microscopes and energy dispersive spectroscopy, etc. The surface Zeta potential of the films was investigated by electrokinetic analyzer for solid surface analysis. The results reveal that the films have three-dimensional cubic mesostructure. The mesoporous silica films are covered with a thin CHA layer after being soaked in a simulated body fluid (1.5 SBF) for 14 d, indicating its good bioactivity. The unique mesostructure and the presence of abundant electronegative silanol groups in physiological solution may be responsible for the bioactivity.

Key words: pure titanium, cubic phase, mesoporous silica thin films, dip-coating, carbonated hydroxyapatite

CLC Number:

TQ127

ZHANG Zhen-Rong, YAO Yi-Yuan, LUO Kai, WAN Long, LIU Xuan-Yong. Cubic Mesoporous Silica Thin Films Coated on Titanium to Induce Carbonated Hydroxyapatite Deposition[J]. Journal of Inorganic Materials, 2015, 30(7): 725-731.

Figures/Tables 10

Fig. 1 Small-angle X-ray diffraction patterns of the films peeled off from the as-synthesized (a), extracted (b) and calcined (c) samples

Fig. 2 FTIR spectra of the mesoporous silica films peeled off from the as-synthesized (a), extracted (b) and calcined (c) samples

Fig. 3 Nitrogen adsorption-desorption isotherms and the corresponding pore size distribution curve (inset) of the film peeled off from the extracted sample

Fig. 4 HRTEM images and Fourier transform of the extracted films (a) One-dimensional lattice and diffraction spot; (b) Two-dimensional lattice and hexagonal diffraction spot; (c) Three-dimensional lattice and matrix diffraction spot, and (d) EDS analysis

Fig. 5 Surface morphologies of the extracted films on Ti substrate by dip-coating method for one time (a), two times (b), three times (c) and EDS pattern of the sample in (d)

Fig. 6 Surface morphologies and EDS analysis of the deposition on the mesoporous silica films after soaking in 1.5SBF for 14 d (a) Surface morphologies of the deposition on the films at low magnification, (a1) The thin layer with needle-like formation covering the films, (a2) The Ca-P layer with spherical formation gathering on the thin layer, (a3) The same surface at higher magnification, a spherical texture with needle-like formation can be observed, and (b) EDS spectrum of spherical formation

Fig. 7 FTIR spectra of (a) mesoporous silica films peeled off the substrate, (b) nano-hydroxyapatite powder, and (c) the deposition on the films soaked in 1.5SBF for 14 d

Fig. 8 XRD patterns of mesoporous silica films peeled off the substrate (a), nano-hydroxyapatite powder (b), and the deposition peeled off the films (c)

Fig. 9 Zeta potential vs. electrolyte’s pH of the mesoporous silica films

Fig. 10 Schematic illustration for the growth of carbonated hydroxyapatite layer on the mesoporous silica films after soaking in a simulated body fluid

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