Abstract: The ultrafine bioactive glass powder (uSBG) with particle size less than 1μm was prepared by sol-gel and wet grinding methods. The biomineralization properties in SBF of the two powders (uSBG and SBG) were analyzed and compared by using FTIR, XRD, SEM. The results indicate that hydroxyl-carbonate apatite (HCA) forms on the surface of the two samples and biomineralization rate of uSBG is prompted significantly by wet grinding. pH value of SBF solution immersed uSBG for different times is lower than that of SBF for SBG, and ICP tests show that the releasing rules of ions are different between uSBG and SBG.

Key words: sol-gel, bioactive glass, wet grinding method, simulated body fluid (SBF)