高级检索
无机材料学报

无机材料学报

• 研究论文 • 上一篇    下一篇

β-磷酸三钙/硅酸钙复合生物陶瓷的制备及性能研究

林开利, 常江, 卢建熙, 高建华, 曾毅   

  1. 中国科学院上海硅酸盐研究所, 上海 200050
  • 收稿日期:2005-11-18 修回日期:2006-01-11 出版日期:2006-11-20 网络出版日期:2006-11-20

Fabrication and Characterization of β-Ca 3(PO 4) 2/CaSiO 3 Composite Bioceramics

LIN Kai-Li, CHANG Jiang, LU Jian-Xi, GAO Jian-Hua, ZENG Yi   

  1. Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China
  • Received:2005-11-18 Revised:2006-01-11 Published:2006-11-20 Online:2006-11-20

PDF (PC)

1610

被引次数

18

摘要：

以β-磷酸三钙/硅酸钙(β-TCP/CS)纳米复合粉体为原料, 制备了质量比为50:50的β-TCP/CS复合生物陶瓷. 研究表明, 1150℃烧结5h得到的样品强度最好, 其致密度>96%, 晶粒尺寸约120nm, 强度达126MPa、同人体致密骨相当; 复合陶瓷在模拟体液中浸泡1天表面就全部被类骨羟基磷灰石层覆盖住, 28天的降解率达10.1%, 具有良好的生物活性和降解性. 研究结果显示β-TCP/CS复合生物陶瓷有望作为强度较好的可降解生物活性硬组织修复材料.

关键词: β-磷酸三钙/硅酸钙, 复合生物陶瓷, 力学强度, 生物活性, 降解性

Abstract: β-Ca 3(PO 4) 2/CaSiO 3 (β-TCP/CS) composite bioceramics with weight ratio of 50:50 were fabricated by using the β-TCP/CS nano-composite powders. The β-TCP/CS composite bioceramics with >96% relative density and 120nm grain size were obtained after sintering at 1150℃ for 5h. The bending strength of the samples reached about 126MPa, which was similar to those of the human cortical bone. After soaking in simulated body fluid for 1 day, the samples were completely covered wity hydroxyapatite layers. The degradability of the
samples reached 10.1% within 28 days in~ vitro. The results suggest excellent
in~ vitro bioactivity and degradability of the β-TCP/CS composite
bioceramics. Therefore, these β-TCP/CS composite bioceramics may be
potential candidates as good mechanical strength, bioactive and degradable
biomaterials for hard tissue repair applications.

Key words: β-trualcium phosphate/calcium silicate, composite bioceramics, mechanical strength, bioactivity, degradabilityend

中图分类号: