阿拉伯树胶对胶原-羟基磷灰石复合材料性能的影响

doi:10.3724/SP.J.1077.2011.00038

无机材料学报 ›› 2011, Vol. 26 ›› Issue (1): 38-42.DOI: 10.3724/SP.J.1077.2011.00038

阿拉伯树胶对胶原-羟基磷灰石复合材料性能的影响

冯文坡¹, 祁元明², 汤克勇¹

郑州大学1. 材料科学与工程学院; 2. 生物工程系郑州450001

收稿日期:2010-01-22 修回日期:2010-03-12 出版日期:2011-01-20 网络出版日期:2010-12-23
作者简介:冯文坡(1971-), 男, 博士研究生. E-mail: fwp238@126.com
基金资助:
国家自然科学基金(20676126, 50973097)

Effects of GumArabic on Properties of Collagen-hydroxyapatite Composite

FENG Wen-Po¹,QI Yuan-Ming², TANG Ke-Yong¹

FENG Wen-Po¹,QI Yuan-Ming², TANG Ke-Yong¹1.College of Materials Science & Engineering, Zhengzhou University, Zhengzhou450001, China; 2. Bioengineering Department, Zhengzhou University, Zhengzhou 450001,China

Received:2010-01-22 Revised:2010-03-12 Published:2011-01-20 Online:2010-12-23
Supported by:
National Nature Science Foundation of China(20676126; 50973097)

摘要/Abstract

摘要： 为改善胶原-羟基磷灰石复合材料的界面结合性能, 将阿拉伯树胶引入该体系中, 以Ca(NO₃)₂·4H₂O、(NH₄)₂HPO₄、酸溶胶原、阿拉伯树胶为原料, 原位合成了胶原-羟基磷灰石/阿拉伯树胶复合材料. 采用FT-IR, XRD, SEM表征材料的晶相结构、化学组成和微观形貌, 研究了阿拉伯树胶对胶原-羟基磷灰石复合材料结构与性能的影响. 结果表明, 阿拉伯树胶改变了胶原-羟基磷灰石复合材料的界面形态与结构; 随阿拉伯树胶含量的增加, 胶原-羟基磷灰石复合材料的晶粒变小, 结晶度降低; 复合材料的吸水性能和体外酶降解能力都显著下降(P<0.01),其机械性能在一定范围内得到提高. 阿拉伯树胶与胶原或胶原-羟基磷灰石之间可能形成了蛋白-多糖复合物, 从而起到了交联作用.

关键词: 复合材料, 胶原-羟基磷灰石复合材料, 阿拉伯树胶, 影响

Abstract: In order to improve the interfacialbonding properties of collagen-hydroxyapatite (Col-HA) composite, gum Arabicwas introduced in the system. Ca(NO₃)₂?4H₂O, (NH₄)₂HPO₄, aciddissolved collagen, and gum Arabic were used as the raw materials to in situ preparecollagen-hydroxyapatite/gum Arabic (Col-HA/Gum A) composite. Crystallite phase,chemical composition, and micro-morphology of the composite were characterizedby XRD, FT-IR, and SEM. The effects of gum Arabic on the structure andproperties of the collagen-hydroxyapatite composite were analyzed. The resultsindicate that both the interface structure and the surface morphology of thecollagen-hydroxyapatite composite are changed by the introduction of gumArabic. With increasing the amount of gum Arabic in the system, the sizes ofthe crystal grain and the crystallinity of the Col-HA composite are decreased.Both the hydrophilic properties and the enzymatic degradation capacity <>invitro of the composite are decreased significantly (P<0.01), whilst the mechanical properties of the composite areimproved in a certain range. Complexes of protein-polysaccharide can be formedbetween the gum Arabic and the collagen or collagen-hydroxyapatite, and the gumArabic can act as a cross-linking agent in the new composite.

Key words: comoposite, collagen-hydroxyapatite composite, gum Arabic, effects

中图分类号:

TB303
TB332

冯文坡, 祁元明, 汤克勇. 阿拉伯树胶对胶原-羟基磷灰石复合材料性能的影响[J]. 无机材料学报, 2011, 26(1): 38-42.

FENG Wen-Po,QI Yuan-Ming, TANG Ke-Yong. Effects of GumArabic on Properties of Collagen-hydroxyapatite Composite[J]. Journal of Inorganic Materials, 2011, 26(1): 38-42.

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阿拉伯树胶对胶原-羟基磷灰石复合材料性能的影响

Effects of GumArabic on Properties of Collagen-hydroxyapatite Composite

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