无机材料学报

• 研究论文 • 上一篇    下一篇

羟基磷灰石生物涂层的复合制备与生物相容性

付涛1; 张玉梅1,2; 憨勇1; 徐可为1   

  1. 1. 西安交通大学金属材料强度国家重点实验室, 西安 710049; 2. 第四军医大学口腔医院修复科, 西安 710032
  • 收稿日期:2000-05-08 修回日期:2000-06-01 出版日期:2001-05-20 网络出版日期:2001-05-20

Duplex Prepared Hydroxyapatite Coating and Its Biocompatibility

FU Tao1; ZHANG Yu-Mei1,2; HAN Yong1; XU Ke-Wei 1   

  1. 1. State Key Laboratory for Mechenical Behavior of Materials; Xi an Jiaotong University; Xi an 710049; China; 2. Department of Prosthetics; School of Dentisty; the Fourth Military Medical University; Xi an 710032; China
  • Received:2000-05-08 Revised:2000-06-01 Published:2001-05-20 Online:2001-05-20

摘要: 采用等离子喷涂CaHPO和水热处理复合制备羟基磷灰石生物涂层,研究了羟基磷灰石涂层的结合强度和溶解性,用成骨细胞考察了生物相容性.结果表明:喷涂涂层由CaHPO4、β-Ca和α-Ca(PO组成,其相比例、结晶性和形貌取决于喷涂电流和喷涂距离;喷涂涂层经过水热处理可转化为针状结晶的缺钙羟基磷灰石;这种羟基磷灰石涂层具有高的结合强度和稳定性,与成骨细胞的生物相容性良好.

关键词: 羟基磷灰石, 生物涂层, 等离子喷涂, 水热合成, 细胞实验

Abstract: The hydroxyapatite coating was hydrothermally prepared from plasma sprayed CaHPO4 coating and its
bonding strength and solubility were studied. The osteoblast culture test was also produced in order to examine the biocompatibility of the coating.
The as-sprayed coating consists of CaHPO4, β-Ca2P2O7 and α-Ca3(PO4)2, and the phase ratio, crystallity and morphology
are dependent on spraying current and stand-off distance. The as-spayed coating can be converted to calcium-deficient hydroxyapatite coating with
needle-like crystals by hydrothermal treatment. The hydrothermally synthesized hydroxyapatite coating having high bonding strength and stability, possesses good
biocompatibility with the osteoblast.

Key words: hydroxyapatite, biocoating, plasma spray, hydrothermal synthesis, cell test

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